Hematidrosis (also called
hematohidrosis) is a very
rare condition in which a human sweats blood. It may occur when a person
is suffering extreme levels of stress, for example, facing his or her
own death. Several historical references have been described; notably by
Leonardo da Vinci: describing a soldier who sweated blood before
battle, men unexpectedly given a death sentence, as well as descriptions
in the Bible, that Jesus experienced hematidrosis when he was praying
in the garden of Gethsemane (
Luke 22:43-44).
There are a few names and conditions which may pertain to this, such
as hematochromatosis, or staining of tissues with blood pigment.
Hemochromatosis a disorder due to deposition of hemosiderin in the
parenchymal cells, causing tissue damage and dysfunction of the liver,
pancreas, heart, and pituitary. Other clinical signs include bronze
pigmentation of skin, arthropathy, diabetes, cirrhosis,
hepatosplenomegaly, hypogonadism, and loss of body hair. Full
development of the disease among women is restricted by menstruation and
pregnancy.
There are varying degrees of hemochromatosis, as described below.
Acquired hemochromatosis
Results from blood transfusions or excessive dietary iron, or secondary to other disease, e.g.,
thalassemia or
sideroblastic anemia; called also secondary hemochromatosis.
Genetic, hereditary, and idiopathic hemochromatosis
An
autosomal recessive disorder of iron metabolism associated with a gene tightly linked to the A locus of the
human leukocyte antigens
(HLA). complex on chromosome 6; iron accumulation is lifelong, with
symptoms appearing usually in the fifth or sixth decades of life.
Neonatal and perinatal hemochromatosis
A rare
fulminant
disease of the liver, of unknown cause, characterized by massive
deposition of iron in the liver, pancreas, heart, and endocrine glands;
symptoms are those of
neonatal hepatitis and appear in utero or within the first week of life, with death usually occurring by 4 months of age.
See also
References
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